Both parasites are hermaphroditic, have similar life cycles, and cause similar clinical manifestations in. Most of the areas with high endemicity of human fascioliasis involve f. In turkey, 53 cases of human fascioliasis were reported from the mediterranean region between 1998 and 2003 334, and the seroprevalence of f. Fascioliasis article about fascioliasis by the free. Fascioliasis definition of fascioliasis by the free dictionary. These two foodborne trematodes usually infect domestic ruminants and cause important economic losses of sheep, goats, and cattle in commercial herds 1. Fascioliasis, a food or waterborne trematodiasis due to infection by fasciola hepatica fh or f. Fascioliasis an infection of the liver caused by two trematodes fasciola hepatica and f. Cure rates are high, while adverse reactions following treatment are usually temporary and mild. Fasciola hepatica, or common liver fluke, is the agent of fascioliasis, a disease. Ppt fasciola hepatica powerpoint presentation free to. Fascioliasis is a disease of ruminants caused by two major parasitic trematodes, fasciola hepatica and f. Association of fasciola hepatica infection with liver. Nitazoxanide 500 mg orally twice a day for 7 days may be effective, but the data are limited.
Fasciola is 1530mm long, flat, liver trematode that is endemic in sheepraising regions. Prevalence of bovine fasciolosis and economic importance in. Association of fasciola hepatica infection with liver fibrosis. Although extremely rare in western europe, it is often observed in developing countries. Causative agents of fascioliasis, how do we get this infection. Fascioliasis is caused by two species of parasitic flatworms or trematodes that mainly affect the liver. Humans are incidental hosts and become infected by ingesting contaminated watercress or water. Fasciola hepatica and fasciola gigantica gmch,chandigarh.
Fasciola hepatica is a large liver fluke that lives in the bile ducts of its mammalian. Both parasites are hermaphroditic, have similar life cycles, and cause similar clinical manifestations in humans. Adw doesnt cover all species in the world, nor does it include all the latest scientific information about organisms we describe. It is caused by the common liver fluke and giant liver fluke, which parasitize man, cattle, sheep, swine, and other animals. Immunodetection of fasciola gigantica circulating antigen in. Statistically significant variation was observed in the prevalence of fasciolosis among animals with medium 50% and good 32. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Winner of the standing ovation award for best powerpoint templates from presentations magazine.
Fascioliasis article about fascioliasis by the free dictionary. Epidemiological studies on fasciolosis in northern tunisia. Fascioliasis is found in all 5 continents, in over 50 countries, especially where sheep or cattle are reared. It belongs to the group of foodborne trematode infections and is a zoonosis, meaning an animal infection that may be transmitted to humans. In sheep, the migratory phase of the parasite produces severe parenchymal disease of the liver for which the parasite is called sheep liver fluke and the disease is known as liver rot. Bithionol is now the drug of choice for fascioliasis. Thus, patients should be asked to follow a liver free diet for several days before their.
Oct 11, 2019 fascioliasis is a waterborne and foodborne zoonotic disease caused by two parasites of class trematoda, genus fasciola. Matured fasciola hepatica dwells in the hepatobiliary system of herbivores or humans and lay eggs, which were released through the feces. Fascioliasis, infection of humans and grassgrazing animals, caused by the liver fluke fasciola hepatica, a small parasitic flatworm that lives in the bile ducts and causes a condition known as liver rot. Nevertheless, longterm veterinary use of triclabendazole has caused appearance of resistance in f. Fasciolosis definition of fasciolosis by medical dictionary. Fascioliasis diagnosis, treatment and control strategy diagnosis. Adult fasciola hepatica flukes grow to become spinyappearing, brown. Imported fasciola hepatica infection in the united states and. Fasciola hepatica is a trematode parasite found throughout europe which affects a range of. Habit and habitat of fasciola hepatica structure of fasciola hepatica. Fascioliasis nord national organization for rare disorders. Is a parasitic flatworm of the class trematoda, phylum platyhelminthes that infects liver of various mammals, including humans. Fascioliasis is found in all continents except antarctica, in over 70 countries, especially where there are sheep or cattle.
Fascioliasis is a parasitic infection typically caused by fasciola hepatica, which is also known as the common liver fluke or the sheep liver fluke. Pdf educational material find, read and cite all the research you need on. Fasciola hepatica material safety data sheet infectious substances section i infectious agent name. The disease caused by the fluke is called fascioliasis also known as fasciolosis.
These two foodborne trematodes usually infect domestic ruminants and cause important economic losses of sheep, goats, and cattle in commercial herds. Bithionol, a halogenated phenol previously used as first line agent for the treatment of fascioliasis in usa is no longer available. A free powerpoint ppt presentation displayed as a flash slide show on id. Jan 31, 2019 fascioliasis is a trematode infection caused by two species of hepatic flukes, fasciola hepatica or fasciola gigantica. The life cycle, transmission, morphology, clinical presentation, and treatment of the f. Fasciola hepatica is a parasite that infects mainly the liver of various mammals, including humans. Fasciolosis is a parasitic worm infection caused by the common liver fluke fasciola hepatica as well as by fasciola gigantica. Triclabendazole as a single dose is also recommended.
Fascioliasis, fasciola hepatica, fasciola gigantica, trematodiasis, neglected tropical diseases, liver fluke. Incidental human fascioliasis, acquired by eating watercress contaminated by sheep or cattle dung, occurs in europe, africa, china, and south america but is rare in the us. Adult fasciola hepatica hydrochloric carmine staining. Hepatic fascioliasis synonyms, hepatic fascioliasis. It infects the livers of various mammals, including humans. Fascioliasis due to fasciola hepatica and fasciola gigantica infection. Other drugs that were used previously and are no longer recommended due to toxicity include emetine, dehydroemetine. The travel and tropical medicine manual fifth edition, 2017. Fascioliasis is caused by infection with the parasitic worms of the genus fasciola, of which fasciola hepatica, found in temperate climates, and fasciola gigantica, found in tropical climates, are the most common. Over the past two decades human fascioliasis has gained notice as a disease of primary importance. Fasciola hepatica sheep liver fluke phylum platyhelminthe class trematoda fasciola gigantica very rarely infects humans. A related parasite, fasciola gigantica, also can infect people. Fascioliasis belongs to the group of foodborne trematode infections and is a zoonosis, meaning an animal infection that may be transmitted to humans.
The disease progresses through four distinct phases. Ppt human fascioliasis powerpoint presentation free to. Fasciola hepatica commonly called sheep liver fluke. Fasciola hepatica bahiya basheer 2nd year mbbs student 2. Hepatic fascioliasis definition of hepatic fascioliasis by the free. It was always considered to be mainly a veterinary disease, and until the 1980s, only sporadic cases were reported in humans. Diagnosis of fascioliasis may be suspected on the basis of the clinical picture, on the anamnestic recall of consuming raw vegetables, on the detection of eosinophilia blood eosinophil count 500 per. Immunodetection of fasciola gigantica circulating antigen.
Fascioliasis definition of fascioliasis by merriamwebster. Fascioliasis is a worldwide anthropozoonotic food and waterborne disease, caused by the trematodes fasciola hepatica and f. Fasciola hepatica the common names are the sheep liver fluke and the common liver fluke. Eggs of fasciola hepatica have been found in mummies, showing that human infection was occurring at least as early as pharaonic times farag. This parasite liver fluke is endemic in many parts of the world including countries from asia, africa, europe and the americas. The parasite is transmitted by consumption of fasciola spp. Hepatic fascioliasis article about hepatic fascioliasis. Apr 21, 2019 human fascioliasis hepatica distomatosis. Definitive hosts of the fluke are cattle, sheep, and buffaloes. Patient may be asymptomatic or presents with jaundice and biliary colic or right hypochondriac pain due to bile duct obstruction with gastrointestinal symptoms. Fascioliasis is a worldwide zoonotic infection caused by liver flukes of the genus fasciola, of which f. Fascioliasis is caused by a parasitic flat worm that primarily affects the liver and bile duct.
Fascioliasis is a disease that affects the liver parenchyma and bile ducts of numerous animals, including humans, which causes economic losses and threatens public health 2. Fascioliasis, sheep liver fluke disease, halzoun, marrara, read more. Hepatic fascioliasis mimicking intrahepatic cholangiocarcinoma 88 int j clin exp med 2017. The disease caused by the fluke is called fascioliasis also kn. The lifecycle of fasciola hepatica fasciola hepatica occurs in the liver of a definitive host and its lifecycle is indirect. Who fascioliasis diagnosis, treatment and control strategy. The eggs are deposited mainly in the bile ducts of. Commonly known as liver flukes, the parasites cause a zoonotic infection that affects domestic herd animals such as cattle, sheep, donkeys, horses, camels, pigs and wild animals. Oct 11, 2019 fasciola, lymnaeids and human fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control.
The disease is a plantborne trematode zoonosis, and is classified as a neglected tropical disease ntd. After brief introductory items hepatics three extensive chapters on human liver fluke disease in cuba caused by fasciola hepatica, the well known european sheep liver fluke now cosmopolitan in its distribution. The drug is given orally in single or multiple doses and has few side effects. Synonyms for hepatic fascioliasis in free thesaurus. Fascioliasis due to fasciola hepatica and fasciola gigantica.
Fascioliasis refers to a zoonosis caused by fasciola hepatica, a trematode infecting herbivores, but also occurs in humans who ingest the metacercaria found in fresh water plants. Mar 26, 2020 as a result of this unclear heptica, flukes in japan are normally referred to as fasciola spp. Fasciola hepatica is a liver fluke that causes fascioliasis, a zoonotic infection that. Sep 16, 2012 fasciola hepatica fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic flatworm of the class trematoda, phylum platyhelminthes that infects the livers of various mammals, including humans. Fascioliasis is a zoonotic disease caused by fasciola species. The content of the website and databases of the national organization for rare disorders nord is ed and may not be reproduced, copied, downloaded or disseminated, in any way, for any commercial or public purpose, without prior written authorization and approval from nord. Fascioliasis is caused by infection with flat worms of the genus fasciola either f. Fasciola hepatica is common in the temperate zones, we are talking about worldwide distribution that you find fasciola hepatica in the temperate zones whereas fasciola gigantica is a parasite dominant or predominant in africa. Chronic infection with fascioliasis can result in pain, abdominal inflammation and the formation of scar tissue and fibrosis in the bile duct, but it is not fatal.
High prevalence rates of fascioliasis has been repeatedly reported in the andean region of south america. Praziquantel, previously used as an alternative drug is no longer recommended due to poor efficacy against fasciola species. Triclabendazole, the only medicine recommended by who against fascioliasis, is active against both immature and adult parasites, and may therefore be employed during the acute and chronic phases. Fascioliasis is among the important parasitic diseases in tropical and subtropical countries which limit productivity of ruminants in particular cattle. Little research has been done with free floating metacercariae, but in human fascioliasis, certain patients have no other reported routes of infection other than ingestion of free floating metacercariae mascoma 2004, morley 2015. Eggs hatch into ciliated larvae miracidia in freshwater, and multiply with. Author summary fascioliasis is a neglected infectious disease caused by the trematode fasciola. It affects humans, but its main host is ruminants such as cattle and sheep. Perkembangan fasciolosis dan pencegahannya di indonesia kurniasih bagian patologi, fakultas kedokteran hewan, universitas gadjah mada cacing hati pertama kali dilukiskan oleh francesco redi pada tahun 1668, diuraikan secara jelas tentang anatominya oleh godvard bidlo pada tahun 1698 dan diberi nama fasciola hepatica oleh linnaeus. New developments in epidemiology, diagnosis, and treatment of fascioliasis.
Fascioliasis definition of fascioliasis by the free. Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode fluke or flatworm, a type of helminth of the class trematoda, phylum platyhelminthes. Fascioliasis is infection with the liver fluke fasciola hepatica. In this article we will discuss about fasciola hepatica. Fasciola hepatica fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic flatworm of the class trematoda, phylum platyhelminthes that infects the livers of various mammals, including humans. Fasciola hepatica definition of fasciola hepatica by. The animal diversity web is an educational resource written largely by and for college students. Article information, pdf download for the pathology of natural fasciola hepatica open epub for the. Fasciola hepatica, also known as the common liver fluke or sheep liver fluke. The trematodes fasciola hepatica also known as the common liver fluke or the sheep liver fluke and fasciola gigantica are large liver flukes f.
Case report diagnosis and management of hepatic fascioliasis. Liver complications in infected humans by this fluke have been. Follow me to a labeled images of fasciola hepatica. The egg the eggs of fasciola hepatica are operculated and average 140. Fascioliasis definition is infestation with or disease caused by liver flukes fasciola hepatica or f. Register for email alerts with links to free fulltext articles access pdfs of free articles manage your interests save searches and receive search alerts. Pdf background fascioliasis is a zoonotic disease caused by fasciola.